Injection form of Dihydroquercetin

Project No. 1

DihydroquercetinInjection preparation in 5 ml ampoules. The content of the main active substance (DHA) is 50 mg in 5 ml ampoule. It is a transparent sterile solution of yellow color in glass ampoules. The drug is designed to reduce the time of acute coronary artery spasm and the treatment of coronary heart disease, the prevention of cardiovascular pathology.

In contrast to the injection form of quercetin (created as a lyophilized form), we have developed a water-soluble form of dihydroquercetin in ampoules with the content of the active 50 and 100 mg. At present, we have developed the technology for production of OTC and prepared a draft pharmaceutical article for Dihydroquercetin. Production of Dihydroquercetin Substance has been arranged.
The technology of preparation of injection solution of water-soluble Dihydroquercetin is based on creation of composition of auxiliary substances permitted for these purposes, which convert Dihydroquercetin into water-soluble form. The uniqueness of the technology lies in the stabilization of Dihydroquercetin in relation to oxygen. This technology can be modified in relation to other water-soluble substances by changing the ratio of auxiliary substances in the composition.

Competitors widely use similar solutions for similar tasks, but they could not find a solution for Dihydroquercetin, as well as for Quercetin, for which the lyophilizate form was developed.

The production of Dihydroquercetin requires: the presence of an ampoule substance licensed in the GMP standard, the presence of a substance licensed in the GMP standard, approved reports of all stages of research: quality module, dossier for the substance, pharmacy for the substance and Dihydroquercetin, production regulations for Dihydroquercetin, preclinical and clinical trials 1 and 2 phases.

The water-soluble form of Dihydroquercetin is widely used in veterinary medicine, food industry, specialized nutrition and production, feed industry and in vegetative fertilizers.

There are no technological risks.

Project status:
Preclinical studies are coming to an end, clinical trials have been started. Preparation for construction of industrial building is in progress.
LLC “DIAFARM SM” is ready to consider various options of partnership with interested companies.

Foods for nutrition of athletes

Project No. 2

Продукты для питания спортсменовThe philosophy of creating specialized products for athletes’ nutrition is to minimize the use of artificially synthesized ingredients. The products we develop are based on many years of scientific research on the effects of natural extracts on the human body and their combination to achieve optimal effects.

Our products are designed for both professional athletes and people who lead active, healthy lives.
Scientific basis:


Sports Research Institute. 2011.

This year the research work of the Research Institute of Sports RSUFKSMIT was completed: “Influence of the preparation “Taxifolin” (dihydroquercytin) on the physical performance of highly professional athletes in cyclic sports” (Director of the Research Institute of Sports Doctor of Biological Sciences, Professor S.P.Levushkin, head of the topic: Candidate of Medical Sciences, Professor S.K.Sarsania). It was concluded that the urgent effect of taking the drug DHA (dihydroquercetin, taxifolin) has a tendency to increase physiological indicators characterizing the aerobic capacity of muscles, which becomes reliable with long-term adaptation. At long-term use of the preparation there is a tendency to faster recovery after physical activity, which is expressed in acceleration of recovery of HCV and variability of dispersion of cardiointervals to the initial level of load.

2. studies of DIGIDROKVERCETIN (Taxifolin) were conducted during training and preparation for international competitions of sportsmen of the Russian Olympic teams in 2008 under the guidance of a member of the Medical Commission of the Russian Olympic Committee, Doctor of Medical Sciences, Professor of the Department of Therapeutic Physical Education, Sports Medicine and Physical Education of the Russian State Medical University Parastayev S.A. The conclusion is made that DIGIDROKVERCETIN (Taxifolin) shows a high degree of efficiency in the application of the professional therapy.

For our products, a formulation has been developed using a number of natural extracts supplementing the action of Dihydroquercetin.